Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568330 | 0.87 | TDP1 (0.59) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1931406 | 0.81 | ALDH1A1 (0.51) | MAPK1NPBWR1ALDH1A1MAPTMEN1 | |
| SCHEMBL9798383 | 0.81 | MAPK1 (0.62) | MAPK1NPBWR1ALDH1A1MAPTMEN1 | |
| SCHEMBL6703081 | 0.79 | MAPK1 (0.88) | MAPK1NPBWR1ALDH1A1MAPTMEN1 | |
| SCHEMBL9568354 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAHIF1ATHRB | |
| SCHEMBL9568408 | 0.78 | ALDH1A1 (0.55) | MAPK1NPBWR1ALDH1A1MAPTMEN1 | |
| SCHEMBL6573092 | 0.78 | PTGS2 (0.55) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL11314219 | 0.78 | PTGS1 (0.54) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4910527 | 0.77 | ALDH1A1 (0.67) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27765 | 0.77 | MAPK1 (1.00) | MAPK1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |