SCHEMBL9568484

SCHEMBL9568484

C=CC(=O)Nc1cccc(CCC)c1S(N)(=O)=O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
EGFR P00533 1/20 0.38
RORC P51449 6/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
TGM2 P21980 2/20 0.37
FGFR4 P22455 2/20 0.35
JAK3 P52333 2/20 0.35
BTK Q06187 5/20 0.35
TEC P42680 1/20 0.35
TXK P42681 1/20 0.35
BMX P51813 1/20 0.35
ITK Q08881 1/20 0.35
ERBB4 Q15303 1/20 0.35
PLA2G7 Q13093 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8361130 0.80 POLB (0.45) EGFRRORCCA1CA2TGM2
SCHEMBL9568523 0.74 THRB (0.54) THRATHRBCA1CA2
SCHEMBL8359087 0.74 MEN1 (0.47) EGFRRORCCA1CA2TGM2
SCHEMBL9568774 0.73 THRB (0.45) THRATHRBEGFRRORCCA1
SCHEMBL7178423 0.73 EGFR (0.52) EGFRTGM2
SCHEMBL10437098 0.72 THRA (0.50) THRATHRBEGFRTGM2
SCHEMBL9838006 0.72 EGFR (0.44) THRATHRBEGFRRORCTGM2
SCHEMBL28738658 0.71 THRA (0.56) THRATHRBEGFRTGM2
SCHEMBL28166963 0.71 THRA (0.43) THRATHRBEGFRRORCTGM2
SCHEMBL9399515 0.71 TGM2 (0.42) RORCTGM2BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed