SCHEMBL9568615

SCHEMBL9568615

C=CC(=O)Oc1ccc(S(=O)(=O)NCC(C)C)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
LMNA P02545 3/20 0.50
HSP90AA1 P07900 1/20 0.50
HSP90AB1 P08238 1/20 0.50
PDK1 Q15118 1/20 0.50
PDK2 Q15119 1/20 0.50
PDK3 Q15120 1/20 0.50
PDK4 Q16654 1/20 0.50
THRB P10828 2/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
GBA1 P04062 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568620 0.84 MEP1B (0.46) ALDH1A1LMNAHSP90AA1HSP90AB1PDK1
SCHEMBL9568830 0.84 THRB (0.56) ALDH1A1LMNATHRBMEN1KMT2A
SCHEMBL3248081 0.82 ALDH1A1 (0.51) ALDH1A1LMNAHSP90AA1HSP90AB1PDK1
SCHEMBL9568797 0.82 ALDH1A1 (0.59) ALDH1A1LMNATHRBMEN1KMT2A
SCHEMBL9568766 0.80 THRB (0.55) ALDH1A1LMNATHRBMEN1KMT2A
SCHEMBL9568639 0.80 SMN1; SMN2 (0.53) ALDH1A1LMNATHRBMEN1KMT2A
SCHEMBL9568741 0.79 SMN1; SMN2 (0.58) ALDH1A1LMNATHRBCA1CA2
SCHEMBL8029643 0.77 ALDH1A1 (0.65) ALDH1A1LMNACA1CA2SMN1; SMN2
SCHEMBL27403594 0.77 THRB (0.46) LMNATHRBCA1CA2SMN1; SMN2
SCHEMBL7754150 0.76 ALDH1A1 (0.57) ALDH1A1LMNAHSP90AA1HSP90AB1PDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed