SCHEMBL9568667

SCHEMBL9568667

C=CC(=O)Nc1cccc(NS(=O)(=O)CC)c1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 4/20 0.55
NPC1 O15118 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 2/20 0.46
NAMPT P43490 1/20 0.46
EGFR P00533 3/20 0.45
JAK3 P52333 1/20 0.45
GSTO1 P78417 1/20 0.45
BTK Q06187 1/20 0.44
LPAR1 Q92633 1/20 0.44
LPAR2 Q9HBW0 1/20 0.44
ITK Q08881 2/20 0.44
LMNA P02545 1/20 0.43
BRD4 O60885 1/20 0.43
ACKR3 P25106 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568629 0.85 TGM2 (0.58) TGM2ALDH1A1HPGDEGFRGSTO1
SCHEMBL9568569 0.84 HPGD (0.65) TGM2HPGDGSTO1LMNA
SCHEMBL4103284 0.82 TGM2 (0.76) TGM2EGFRJAK3BTKLPAR1
SCHEMBL396066 0.81 BTK (0.50) TGM2HPGDNAMPTEGFRJAK3
SCHEMBL396065 0.79 TDP1 (0.59) NPC1ALDH1A1HPGDLMNA
SCHEMBL23988636 0.79 EGFR (0.49) TGM2EGFRBTKLMNA
SCHEMBL9568677 0.78 TGM2 (0.58) TGM2ALDH1A1HPGDBTKBRD4
SCHEMBL9568733 0.78 BTK (0.63) TGM2ALDH1A1BTKLMNA
SCHEMBL22600367 0.78 TGM2 (0.65) TGM2EGFRJAK3BTKLPAR1
SCHEMBL6355891 0.78 TGM2 (0.65) TGM2ALDH1A1EGFRLPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed