Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690103 | 0.85 | ALDH1A1 (0.43) | MAPK1CYP1A2CYP2C19ALDH1A1HPGD | |
| SCHEMBL9568847 | 0.83 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL9568925 | 0.78 | ALDH1A1 (0.54) | MAPK1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL9568758 | 0.76 | ALDH1A1 (0.41) | MAPK1L3MBTL1ALDH1A1HPGDMAPT | |
| SCHEMBL9568705 | 0.76 | KDM4E (0.41) | MAPK1CYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL9568731 | 0.74 | MAPK1 (0.41) | MAPK1L3MBTL1ALDH1A1HPGDMAPT | |
| SCHEMBL9568841 | 0.71 | KMT2A (0.51) | MAPK1L3MBTL1CYP3A4ALDH1A1HPGD | |
| SCHEMBL9568853 | 0.71 | ALDH1A1 (0.65) | MAPK1L3MBTL1ALDH1A1HPGDMAPT | |
| SCHEMBL9557277 | 0.69 | MAPK1 (0.41) | MAPK1L3MBTL1ALDH1A1HPGDMAPT | |
| SCHEMBL9568725 | 0.68 | POLB (0.40) | MAPK1L3MBTL1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262433-A | Antidiabetic agents | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0528277-A1 | Tetrazoleacetic acid derivatives aldose reductase inhibitors | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1993-02-24 | — | — | EP | disclosed |