Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983231 | 0.84 | HDAC1 (0.48) | HDAC1MEN1KMT2APOLBSAE1 | |
| SCHEMBL9569793 | 0.81 | EPHX2 (0.48) | HDAC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL9569786 | 0.80 | HDAC1 (0.44) | HDAC1MAPTNPC1GAAFBP1 | |
| SCHEMBL9836719 | 0.73 | CA2 (0.58) | HDAC1GAAALOX15TPSAB1CA2 | |
| SCHEMBL19869285 | 0.73 | NLRP3 (0.53) | FBP1 | |
| SCHEMBL5048183 | 0.72 | HDAC1 (0.60) | HDAC1POLBGAAGHSRTPSAB1 | |
| SCHEMBL5047130 | 0.72 | HDAC1 (0.56) | HDAC1KMT2ARAB9ATP53NPC1 | |
| SCHEMBL9920101 | 0.72 | P2RY12 (0.52) | HDAC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL18029666 | 0.72 | NLRP3 (0.55) | FBP1 | |
| SCHEMBL2175211 | 0.71 | FBP1 (0.75) | FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560554-A2 | Antitumor compositions and methods of treatment | ELI LILLY AND COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5169860-A | Benzofuran or benzothiophene arylsulfonylureas | ELI LILLY AND COMPANY (US) | 1992-12-08 | — | — | US | disclosed |