Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 16/20 | 0.43 |
| ▸ | CA1 | P00915 | 12/20 | 0.43 |
| ▸ | CA12 | O43570 | 9/20 | 0.43 |
| ▸ | CA4 | P22748 | 8/20 | 0.43 |
| ▸ | CA5A | P35218 | 8/20 | 0.43 |
| ▸ | CA7 | P43166 | 8/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569770 | 0.69 | MAOB (0.44) | MAOBMAOAKDM4ENPC1RAB9A | |
| SCHEMBL31287831 | 0.69 | SMN1; SMN2 (0.56) | LMNAPKMCA2CA1CA12 | |
| SCHEMBL1743537 | 0.69 | SMN1; SMN2 (0.56) | LMNAPKMCA2CA1CA12 | |
| SCHEMBL9839080 | 0.69 | LMNA (0.82) | LMNAPKMCA2CA1CA12 | |
| SCHEMBL2182261 | 0.68 | LMNA (0.50) | LMNAALPLALPIPKMCA2 | |
| SCHEMBL28268664 | 0.67 | L3MBTL1 (0.49) | LMNAPKMCA2CA1CA12 | |
| SCHEMBL1655877 | 0.66 | FLT3 (0.50) | CA2CA12MAOBCA9MAOA | |
| SCHEMBL9569769 | 0.66 | CA2 (0.47) | CA2CA1CA12CA4CA5A | |
| SCHEMBL9075377 | 0.65 | CA2 (0.51) | LMNAALPLALPIPKMCA2 | |
| SCHEMBL12278485 | 0.65 | PIM1 (0.44) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560554-A2 | Antitumor compositions and methods of treatment | ELI LILLY AND COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5169860-A | Benzofuran or benzothiophene arylsulfonylureas | ELI LILLY AND COMPANY (US) | 1992-12-08 | — | — | US | disclosed |