Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297127 | 0.79 | GABRA1 (0.56) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL4243158 | 0.78 | HSD17B10 (0.55) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL9569813 | 0.75 | LMNA (0.42) | HSD17B10KDM4EHPGDNSD2LMNA | |
| SCHEMBL22908991 | 0.72 | RORC (0.51) | ALDH1A1HSD17B10KDM4EHPGDSERPINE1 | |
| SCHEMBL5797761 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL24672944 | 0.72 | LMNA (0.52) | ALDH1A1HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL29567634 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL9719512 | 0.71 | HSD17B10 (0.44) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL9719517 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL9549613 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EHPGDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524019-A1 | Hydraulic cement mixtures containing (dialkanol)aminoalkylphenols | W.R. Grace & Co.-Conn. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5102467-A | Adding a (dialkanol)aminomethyl phenol to enhance setting strength | W.R. GRACE & CO.-CONN. (US) | 1992-04-07 | — | — | US | disclosed |