Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570473 | 0.96 | PDE3B (0.34) | CPB2PDE2APDE3BPDE3A | |
| SCHEMBL22317590 | 0.79 | LMNA (0.41) | CPB2 | |
| SCHEMBL9597539 | 0.78 | ADORA2A (0.37) | CPB2PDE2APDE3BPDE3A | |
| SCHEMBL31265577 | 0.73 | PDE3B (0.33) | PDE2APDE3BPDE3A | |
| SCHEMBL31265576 | 0.73 | PDE3B (0.33) | PDE2APDE3BPDE3A | |
| SCHEMBL20536635 | 0.73 | NPC1 (0.45) | CPB2 | |
| SCHEMBL13326541 | 0.70 | — | — | |
| SCHEMBL20536189 | 0.69 | MEN1 (0.43) | CPB2PDE2APDE3BPDE3A | |
| SCHEMBL11845875 | 0.67 | CYP11B2 (0.47) | — | |
| SCHEMBL21457983 | 0.66 | DGAT1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |