SCHEMBL9570889

SCHEMBL9570889

CC1Cc2cc(C(COCc3ccc(F)c(Oc4ccccc4)c3)C(F)(F)F)ccc2O1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 2/20 0.33
RXFP1 Q9HBX9 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
PDE2A O00408 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
RAB9A P51151 1/20 0.30
DUT P33316 1/20 0.30
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570782 0.83 GRM5 (0.33) RAB9AFFAR1
SCHEMBL9570626 0.83 HIF1A (0.34) DUTFFAR1
SCHEMBL9570936 0.82 LMNA (0.39) TDP1KDM4ENPSR1
SCHEMBL9570878 0.82 MAPK14 (0.34) DUTFFAR1
SCHEMBL9570666 0.81 TACR1 (0.35) DUTFFAR1
SCHEMBL9560456 0.81 MAPK14 (0.35) RAB9ADUTFFAR1
SCHEMBL9570739 0.80 FFAR1 (0.34) DUTFFAR1
SCHEMBL9561249 0.79 FFAR1 (0.40) TDP1KDM4EFFAR1
SCHEMBL9570693 0.79 TACR1 (0.36) DUTFFAR1
SCHEMBL9570632 0.79 DUT (0.35) KDM4ERAB9ADUTFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed