Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16316826 | 1.00 | FAAH (0.68) | FAAHLMNASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL9885419 | 1.00 | FAAH (0.68) | FAAHLMNASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL7491784 | 0.98 | LMNA (0.70) | FAAHLMNASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL3223930 | 0.95 | LMNA (0.74) | FAAHLMNASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL9570672 | 0.93 | ALDH1A1 (0.75) | FAAHLMNASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL9570550 | 0.93 | ALDH1A1 (0.75) | FAAHLMNASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL18405957 | 0.92 | FAAH (0.63) | FAAHLMNASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL5820622 | 0.89 | LMNA (0.67) | FAAHLMNASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL1133893 | 0.88 | KMT2A (0.74) | FAAHLMNASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL10802880 | 0.88 | ALDH1A1 (0.77) | FAAHLMNASMN1; SMN2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207222-B2 | Nitric oxide releasing derivatives of paracetamol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-26 | — | — | US | disclosed |
| US-20100234472-A1 | NITRIC OXIDE RELEASING DERIVATIVES OF PARACETAMOL | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2010-09-16 | — | — | US | disclosed |
| WO-2009024998-A1 | NITRIC OXIDE RELEASING DERIVATIVES OF PARACETAMOL | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-02-26 | — | — | WO | disclosed |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234472-A1 | NITRIC OXIDE RELEASING DERIVATIVES OF PARACETAMOL | NOS2, NOS3, NOS1 | FAAH 1072/4885LMNA 4730/4885SMN1; SMN2 4739/4885 |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | FAAH 1086/4885LMNA 4386/4885SMN1; SMN2 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.