Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096307 | 0.98 | ALDH1A1 (0.67) | ALDH1A1KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL22930926 | 0.94 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL3102351 | 0.94 | ALDH1A1 (0.69) | ALDH1A1KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL9570672 | 0.92 | ALDH1A1 (0.75) | ALDH1A1KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL9570550 | 0.92 | ALDH1A1 (0.75) | ALDH1A1KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL2435473 | 0.89 | ALDH1A1 (0.71) | ALDH1A1KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL10802880 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL9885419 | 0.86 | FAAH (0.68) | ALDH1A1KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL16316826 | 0.86 | FAAH (0.68) | ALDH1A1KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL8733277 | 0.86 | FAAH (0.68) | ALDH1A1KMT2ALMNAMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188245-B1 | Nitric oxide releasing derivatives of paracetamol | COUNCIL SCIENT IND RES (IN) | 2013-11-06 | — | — | EP | disclosed |
| US-8207222-B2 | Nitric oxide releasing derivatives of paracetamol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-26 | — | — | US | disclosed |
| US-8207222-B2 | Nitric oxide releasing derivatives of paracetamol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-26 | — | — | US | disclosed |
| US-8207222-B2 | Nitric oxide releasing derivatives of paracetamol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-26 | — | — | US | disclosed |
| US-20100234472-A1 | NITRIC OXIDE RELEASING DERIVATIVES OF PARACETAMOL | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2010-09-16 | — | — | US | disclosed |
| US-20100234472-A1 | NITRIC OXIDE RELEASING DERIVATIVES OF PARACETAMOL | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2010-09-16 | — | — | US | disclosed |
| US-20100234472-A1 | NITRIC OXIDE RELEASING DERIVATIVES OF PARACETAMOL | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2010-09-16 | — | — | US | disclosed |
| EP-2188245-A1 | NITRIC OXIDE RELEASING DERIVATIVES OF PARACETAMOL | Council Of Scientific&industrial Research (IN) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009024998-A1 | NITRIC OXIDE RELEASING DERIVATIVES OF PARACETAMOL | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234472-A1 | NITRIC OXIDE RELEASING DERIVATIVES OF PARACETAMOL | NOS2, NOS3, NOS1 | ALDH1A1 604/4885KMT2A 4537/4885LMNA 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.