Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 2/20 | 0.41 |
| ▸ | NPY4R | P50391 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024843 | 0.73 | TFPI2 (0.58) | TFPI2NPY4RNOTUMHTR3EHTR3B | |
| SCHEMBL31435509 | 0.73 | TFPI2 (0.58) | TFPI2NPY4RNOTUMHTR3EHTR3B | |
| SCHEMBL9570886 | 0.73 | TFPI2 (0.36) | TFPI2NPY4RNOTUMTSHRRAB9A | |
| SCHEMBL6059869 | 0.70 | HTR3A (0.44) | TFPI2NPY4RNOTUMHTR3EHTR3B | |
| SCHEMBL9570724 | 0.67 | ADRA1A (0.46) | TFPI2NPY4RNOTUMHTR3EHTR3B | |
| SCHEMBL2078057 | 0.63 | NOTUM (0.59) | TFPI2NPY4RNOTUMHTR3EHTR3B | |
| SCHEMBL29506395 | 0.61 | NOTUM (1.00) | TFPI2NPY4RNOTUMHTR3EHTR3B | |
| SCHEMBL28471307 | 0.61 | NOTUM (0.66) | TFPI2NPY4RNOTUMHTR3EHTR3B | |
| SCHEMBL41252 | 0.61 | NOTUM (1.00) | TFPI2NPY4RNOTUMHTR3EHTR3B | |
| SCHEMBL14220747 | 0.61 | TFPI2 (0.62) | TFPI2NPY4RTSHRRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532754-A1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-24 | — | — | EP | claimed |