Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 5/20 | 0.46 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435509 | 0.76 | TFPI2 (0.58) | TFPI2NPY4RNOTUMHTR3EHTR3B | |
| SCHEMBL7024843 | 0.76 | TFPI2 (0.58) | TFPI2NPY4RNOTUMHTR3EHTR3B | |
| SCHEMBL8985233 | 0.73 | ADRA1A (0.53) | ADRA1ANOTUMADRA1DADRA1BNAMPT | |
| SCHEMBL16112524 | 0.72 | ADRA1A (0.48) | ADRA1AADRA1DADRA1BNAMPTCDK9 | |
| Hydrochloric Acid SCHEMBL31132960 | 0.72 | ADRA1A (0.51) | ADRA1ANOTUMADRA1DADRA1BL3MBTL1 | |
| SCHEMBL6059869 | 0.70 | HTR3A (0.44) | ADRA1ATFPI2NPY4RNOTUMHTR3E | |
| SCHEMBL24424305 | 0.69 | ADRA1A (0.49) | ADRA1AADRA1DADRA1BTSHRNAMPT | |
| SCHEMBL21674895 | 0.69 | BRD4 (0.61) | ADRA1ANOTUMNAMPT | |
| SCHEMBL9570719 | 0.67 | TFPI2 (0.41) | TFPI2NPY4RNOTUMHTR3EHTR3B | |
| SCHEMBL23641525 | 0.67 | ADRA1A (0.40) | ADRA1AADRA1DADRA1BNAMPTCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532754-A1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-24 | — | — | EP | claimed |
| EP-0532754-A1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |