Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561901 | 0.81 | CCR6 (0.56) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9561922 | 0.76 | CCR6 (0.51) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9572008 | 0.76 | APAF1 (0.45) | APAF1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9572023 | 0.75 | MEN1 (0.51) | APAF1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9572001 | 0.75 | PTPRC (0.50) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9562597 | 0.74 | PTPRC (0.59) | CCR6HKDC1GAAIMPDH2 | |
| SCHEMBL245954 | 0.72 | APAF1 (0.61) | APAF1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL1242685 | 0.72 | MAPT (0.67) | APAF1NPC1RAB9AMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4204888 | 0.71 | APAF1 (0.60) | APAF1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9572005 | 0.70 | CCR6 (0.45) | NPC1RAB9AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |