Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | NSD2 | O96028 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562391 | 0.83 | NTRK1 (0.54) | NPC1RAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL9572000 | 0.76 | APAF1 (0.45) | APAF1NPC1RAB9AMAPTLMNA | |
| SCHEMBL245954 | 0.72 | APAF1 (0.61) | APAF1NPC1RAB9AMAPTLMNA | |
| SCHEMBL1242685 | 0.72 | MAPT (0.67) | APAF1NPC1RAB9AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL4204888 | 0.71 | APAF1 (0.60) | APAF1NPC1RAB9AMAPTLMNA | |
| SCHEMBL9561880 | 0.70 | PTPRC (0.51) | LMNASMN1; SMN2TDP1ALDH1A1HTT | |
| SCHEMBL3852975 | 0.70 | KDM4E (0.51) | MAPTLMNASMN1; SMN2TDP1NPSR1 | |
| SCHEMBL14788035 | 0.70 | MAPT (0.75) | APAF1NPC1RAB9AMAPTLMNA | |
| SCHEMBL9572015 | 0.69 | RAB9A (0.43) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9562520 | 0.69 | NTRK1 (0.51) | MAPTLMNASMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |