Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706016 | 0.89 | ALDH1A1 (0.43) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL9367679 | 0.89 | HPGD (0.44) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL9706010 | 0.89 | HPGD (0.44) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL8782005 | 0.88 | ALDH1A1 (0.43) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL9354128 | 0.87 | LOXL2 (0.48) | HPGDLOXLOXL2 | |
| SCHEMBL8782221 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2 | |
| SCHEMBL9566743 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL9706102 | 0.81 | LOXL2 (0.46) | HPGDGAALOXLOXL2NPC1 | |
| SCHEMBL9706023 | 0.81 | LOXL2 (0.46) | HPGDLOXLOXL2SMN1; SMN2 | |
| SCHEMBL9572972 | 0.81 | LOXL2 (0.46) | HPGDLOXLOXL2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541042-A1 | 2,4- and 2,5-pyridine-dicarboxylic acid derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |