Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706010 | 0.95 | HPGD (0.44) | HPGDMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9572972 | 0.93 | LOXL2 (0.46) | HPGDLOXLOXL2NPC1RAB9A | |
| SCHEMBL9572913 | 0.89 | ALDH1A1 (0.43) | HPGDMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9706016 | 0.88 | ALDH1A1 (0.43) | HPGDMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9706102 | 0.88 | LOXL2 (0.46) | HPGDLOXLOXL2NPC1RAB9A | |
| SCHEMBL8782005 | 0.87 | ALDH1A1 (0.43) | HPGDMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9354128 | 0.86 | LOXL2 (0.48) | HPGDLOXLOXL2 | |
| SCHEMBL9706023 | 0.80 | LOXL2 (0.46) | HPGDLOXLOXL2SMN1; SMN2 | |
| SCHEMBL9566818 | 0.79 | ALDH1A1 (0.44) | HPGDMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8781962 | 0.79 | LOXL2 (0.47) | HPGDALDH1A1HTTLOXLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409119-B1 | N,N'-Bis(alkoxy-alkyl)-pyridine-2,4-dicarboxylic acid amides, process for their preparation as well as their use | HOECHST AG (DE) | 1994-04-13 | — | — | EP | disclosed |
| EP-0409119-A1 | N,N'-Bis(alkoxy-alkyl)-pyridine-2,4-dicarboxylic acid amides, process for their preparation as well as their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-23 | — | — | EP | disclosed |