Perchlorate

Perchlorate

SCHEMBL9574136

C[S+](C)c1ccc(O)cc1.[O-][Cl+3]([O-])([O-])[O-]

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.40
CYP3A4 P08684 4/20 0.40
HSD17B10 Q99714 4/20 0.40
ALOX15 P16050 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
RAB9A P51151 3/20 0.40
HIF1A Q16665 3/20 0.40
ALDH1A1 P00352 3/20 0.40
TYR P14679 2/20 0.40
HPGD P15428 2/20 0.40
CA2 P00918 2/20 0.40
MAPT P10636 2/20 0.40
CA3 P07451 2/20 0.40
CA14 Q9ULX7 2/20 0.40
NPC1 O15118 2/20 0.40
KDM4E B2RXH2 2/20 0.40
CA12 O43570 1/20 0.40
GMNN O75496 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245789 0.89 CYP3A4 (0.50) LMNACYP3A4HSD17B10ALOX15MEN1
Hydrochloric Acid SCHEMBL11662665 0.87 CYP3A4 (0.47) LMNACYP3A4HSD17B10ALOX15MEN1
Sulfuric Acid SCHEMBL3625673 0.81 ENPP2 (0.48) LMNACYP3A4HSD17B10ALOX15MEN1
SCHEMBL30217812 0.80 CYP3A4 (0.40) LMNACYP3A4HSD17B10ALOX15MEN1
SCHEMBL29843423 0.80 CYP3A4 (0.40) LMNACYP3A4HSD17B10ALOX15MEN1
Sulfuric Acid SCHEMBL3625678 0.79 LMNA (0.48) LMNACYP3A4HSD17B10ALOX15MEN1
SCHEMBL29714721 0.79 ENPP2 (0.52) LMNACYP3A4HSD17B10ALOX15MEN1
Sulfuric Acid SCHEMBL3625676 0.78 HPGD (0.50) LMNACYP3A4HSD17B10ALOX15MEN1
SCHEMBL9336595 0.78 ENPP2 (0.35) LMNACYP3A4HSD17B10ALOX15MEN1
Perchlorate SCHEMBL8757712 0.77 ACHE (0.42) LMNAHSD17B10RAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0245662-B1 P-HYDROXYPHENYLSULFONIUM SALTS AND THEIR USE IN THE PREPARATION OF ESTERS AND AMIDES SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1991-08-07 EP claimed
EP-0331988-A1 Sulfonium compounds, as well as process for producing active esters and amides used for the production of amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1989-09-13 EP claimed
EP-0245662-A1 p-Hydroxyphenylsulfonium salts and their use in the preparation of esters and amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1987-11-19 EP claimed
US-5216125-A Active ester used for production of acylated amino acids SANSHIN KAGAKU KOGYO CO. LTD. (JP) 1993-06-01 US disclosed
US-5117031-A ACTIVE ESTERS USED FOR PRODUCTION OF ESTERS OR AMIDES AND PROCESS FOR PRODUCING ESTERS OR AMIDES SANSHIN KAGAKU KOGYO CO. LTD. (JP) 1992-05-26 US disclosed
EP-0245662-B1 P-HYDROXYPHENYLSULFONIUM SALTS AND THEIR USE IN THE PREPARATION OF ESTERS AND AMIDES SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1991-08-07 EP disclosed
EP-0331988-A1 Sulfonium compounds, as well as process for producing active esters and amides used for the production of amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1989-09-13 EP disclosed
US-4857656-A Active esters used for production of esters or amides and process for producing esters or amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1989-08-15 US disclosed
EP-0245662-A1 p-Hydroxyphenylsulfonium salts and their use in the preparation of esters and amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1987-11-19 EP disclosed
US-4120866-A REACTING AN AROMATIC COMPOUND WITH A SULFOXIDE BAYER AKTIENGESELLSCHAFT (DE) 1978-10-17 US disclosed