Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL3625678 | 0.93 | LMNA (0.48) | ENPP2LMNACA2CA1CA12 | |
| SCHEMBL29714721 | 0.93 | ENPP2 (0.52) | ENPP2LMNACA2CA1CA12 | |
| Sulfuric Acid SCHEMBL3625676 | 0.88 | HPGD (0.50) | ENPP2LMNACA2CA1CA12 | |
| SCHEMBL285230 | 0.88 | GAA (0.43) | ENPP2LMNACA2CA1CA12 | |
| Trifluoromethanesulfonic Acid SCHEMBL4182001 | 0.86 | KCNH2 (0.43) | ENPP2LMNACA2CA1CA12 | |
| SCHEMBL245789 | 0.85 | CYP3A4 (0.50) | LMNACA2CA1CA12CA9 | |
| SCHEMBL751396 | 0.85 | ACHE (0.46) | ENPP2LMNACA2CA1CA12 | |
| Trifluoromethanesulfonic Acid SCHEMBL30925713 | 0.85 | ENPP2 (0.44) | ENPP2LMNACA2CA1CA12 | |
| SCHEMBL31038961 | 0.85 | ENPP2 (0.44) | ENPP2LMNACA2CA1CA12 | |
| Hydrochloric Acid SCHEMBL11662665 | 0.83 | CYP3A4 (0.47) | LMNACA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344097-B2 | Cationically polymerizable composition and method for controlling cationic polymerization | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20100081785-A1 | Cationically polymerizable composition and method for controlling cationic polymerization | NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) | 2010-04-01 | — | — | US | disclosed |