Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15834836 | 0.83 | KIF11 (0.43) | LMNAELANEGAAKMT2ACYP1A2 | |
| SCHEMBL7064531 | 0.83 | LMNA (0.70) | LMNAALDH1A1GAAKMT2ACYP1A2 | |
| SCHEMBL28239966 | 0.82 | LMNA (0.57) | LMNAALDH1A1ELANEGAAKMT2A | |
| SCHEMBL146180 | 0.82 | LMNA (0.63) | LMNAALDH1A1ELANEGAAKMT2A | |
| SCHEMBL9575401 | 0.82 | KMT2A (0.41) | ALDH1A1ELANEKMT2ACYP1A2ATM | |
| SCHEMBL29303770 | 0.80 | LMNA (0.55) | LMNAALDH1A1ELANEGAAKMT2A | |
| SCHEMBL9575349 | 0.80 | ELANE (0.39) | LMNAELANEKMT2AATM | |
| SCHEMBL9575199 | 0.80 | MEN1 (0.41) | LMNAALDH1A1ELANEKMT2AMAPT | |
| SCHEMBL9575390 | 0.80 | LDHA (0.41) | LMNAALDH1A1ELANEKMT2ARXFP1 | |
| SCHEMBL9575359 | 0.80 | ELANE (0.42) | ELANEBCHEKMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266668-A | Substituted phenyl α-fluoroacrylates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |