Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15834836 | 0.85 | KIF11 (0.43) | KMT2AATMELANESMN1; SMN2KDM4E | |
| SCHEMBL9575359 | 0.82 | ELANE (0.42) | KMT2AELANESMN1; SMN2CYP1A2HPGD | |
| SCHEMBL9575349 | 0.82 | ELANE (0.39) | KMT2AATMELANECA1CA2 | |
| SCHEMBL9575396 | 0.82 | LMNA (0.55) | KMT2AATMELANEALDH1A1CYP1A2 | |
| SCHEMBL6903315 | 0.82 | ELANE (0.59) | KMT2AATMELANEALDH1A1FAAH | |
| SCHEMBL9575390 | 0.82 | LDHA (0.41) | KMT2AATMELANECES2CES1 | |
| SCHEMBL6315158 | 0.81 | ELANE (0.49) | ATMELANEALDH1A1KDM4EHPGD | |
| SCHEMBL9575148 | 0.79 | CYP4F2 (0.41) | CES2CES1CA1 | |
| SCHEMBL9575659 | 0.79 | KIF11 (0.54) | CES2CES1ALDH1A1CA1CA2 | |
| SCHEMBL12636049 | 0.79 | CES2 (0.39) | KMT2AELANECES2CES1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266668-A | Substituted phenyl α-fluoroacrylates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |