Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193226 | 0.88 | KMT2A (0.43) | KMT2AL3MBTL1MAPK1ALDH1A1RAB9A | |
| SCHEMBL9575717 | 0.78 | MAPK1 (0.67) | KMT2AL3MBTL1MAPK1ALDH1A1RAB9A | |
| SCHEMBL19523407 | 0.75 | L3MBTL1 (0.47) | KMT2AL3MBTL1ALDH1A1CASP3HPGD | |
| SCHEMBL31284913 | 0.73 | KMT2A (0.50) | KMT2AL3MBTL1MAPK1ALDH1A1RAB9A | |
| SCHEMBL17127742 | 0.73 | KMT2A (0.50) | KMT2AL3MBTL1MAPK1ALDH1A1RAB9A | |
| SCHEMBL18658571 | 0.73 | KMT2A (0.44) | KMT2AMAPK1ALDH1A1RAB9AHPGD | |
| SCHEMBL9340887 | 0.73 | ALDH1A1 (0.53) | KMT2AMAPK1ALDH1A1RAB9ACASP3 | |
| SCHEMBL4482770 | 0.73 | ALDH1A1 (0.53) | KMT2AL3MBTL1ALDH1A1RAB9ACASP3 | |
| SCHEMBL30377710 | 0.73 | ALDH1A1 (0.53) | KMT2AL3MBTL1ALDH1A1RAB9ACASP3 | |
| SCHEMBL9575755 | 0.72 | MAPK1 (0.59) | KMT2AL3MBTL1MAPK1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |