Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575441 | 0.87 | RPS6KA3 (0.35) | RPS6KA3KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9575559 | 0.85 | ALDH1A1 (0.41) | RPS6KA3KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9575560 | 0.82 | ACHE (0.40) | ALDH1A1MEN1TSHRKMT2AHDAC6 | |
| SCHEMBL9575400 | 0.82 | KDM4E (0.46) | RPS6KA3KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9575434 | 0.76 | CYP1A2 (0.37) | RPS6KA3KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9125548 | 0.75 | — | — | |
| SCHEMBL9371648 | 0.75 | MEN1 (0.57) | RPS6KA3KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9125846 | 0.73 | — | — | |
| SCHEMBL9575536 | 0.71 | ACHE (0.43) | MEN1TSHRKMT2AFLT3FGFR1 | |
| SCHEMBL9575800 | 0.69 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |