Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575565 | 0.87 | RPS6KA3 (0.39) | RPS6KA3ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL9575536 | 0.85 | ACHE (0.43) | BRD4TSHRACHE | |
| SCHEMBL9575800 | 0.85 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10KDM4EADRA1A | |
| SCHEMBL9575434 | 0.84 | CYP1A2 (0.37) | RPS6KA3BRD4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9575559 | 0.79 | ALDH1A1 (0.41) | RPS6KA3ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL9575560 | 0.71 | ACHE (0.40) | ALDH1A1TSHRACHECYP3A4HIF1A | |
| SCHEMBL9019800 | 0.71 | BCHE (0.38) | BRD4HPGDTSHRCYP1A2ACHE | |
| SCHEMBL9845246 | 0.71 | BCHE (0.36) | BRD4HPGDTSHRCYP1A2ACHE | |
| SCHEMBL9575400 | 0.70 | KDM4E (0.46) | RPS6KA3ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL10816876 | 0.70 | PDE3A (0.38) | ALDH1A1HPGDHSD17B10KDM4EADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| CN-1057652-A | A kind of acyclic nucleotide of replacement and method of related intermediates thereof of preparing | HOECHST AG (DE) | 1992-01-08 | — | — | CN | disclosed |