SCHEMBL9575725

SCHEMBL9575725

CCO[Si](CCCOc1ccc(C[C](C)O)cc1)(OCC)OCC

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
LMNA P02545 2/20 0.45
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
PDE4A P27815 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
PLA2G4B P0C869 1/20 0.41
LTB4R Q15722 2/20 0.37
LTB4R2 Q9NPC1 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9575958 0.93 ALDH1A1 (0.41) ALDH1A1LMNAKDM4ECYP1A2CYP2D6
SCHEMBL9575730 0.81 ACACB (0.40) ALDH1A1LMNAKDM4ECYP1A2CYP2D6
SCHEMBL2579282 0.79 KCNA3 (0.54) ALDH1A1SMN1; SMN2HDAC10HDAC6L3MBTL1
SCHEMBL16448439 0.79 ESR1 (0.38) ALDH1A1LMNAKDM4ECYP2D6SMN1; SMN2
SCHEMBL16248363 0.78 ALDH1A1 (0.41) ALDH1A1LMNAKDM4ECYP1A2CYP2D6
SCHEMBL16448438 0.78 LMNA (0.36) ALDH1A1LMNAKDM4ECYP2D6SMN1; SMN2
SCHEMBL16448437 0.78 KDM4E (0.39) ALDH1A1LMNAKDM4ESMN1; SMN2
SCHEMBL16248365 0.76 ALDH1A1 (0.40) ALDH1A1LMNAKDM4ECYP1A2CYP2D6
SCHEMBL20226245 0.76 CYP2D6 (0.59) KDM4ECYP1A2CYP2D6SMN1; SMN2
SCHEMBL16248366 0.76 ALDH1A1 (0.40) ALDH1A1LMNAKDM4ECYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0281941-B1 Coreactive photoinitiators CIBA GEIGY AG (CH) 1993-12-08 EP claimed