Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575725 | 0.93 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL9575960 | 0.84 | ACACB (0.41) | ALDH1A1LMNARARBSMN1; SMN2MEN1 | |
| SCHEMBL9575778 | 0.76 | LMNA (0.37) | ALDH1A1LMNARARBSMN1; SMN2MEN1 | |
| SCHEMBL9575730 | 0.76 | ACACB (0.40) | ALDH1A1LMNASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL9064593 | 0.74 | RARB (0.47) | LMNARARBSMN1; SMN2RARAPLA2G4B | |
| SCHEMBL2579282 | 0.74 | KCNA3 (0.54) | ALDH1A1SMN1; SMN2HDAC10HDAC6RECQL | |
| SCHEMBL16448439 | 0.74 | ESR1 (0.38) | ALDH1A1LMNASMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL16248363 | 0.73 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL16448438 | 0.72 | LMNA (0.36) | ALDH1A1LMNASMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL16448437 | 0.72 | KDM4E (0.39) | ALDH1A1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281941-B1 | Coreactive photoinitiators | CIBA GEIGY AG (CH) | 1993-12-08 | — | — | EP | claimed |