Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575640 | 0.94 | LMNA (0.39) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9064593 | 0.78 | RARB (0.47) | LMNARARBSMN1; SMN2RARAMAPT | |
| SCHEMBL10455828 | 0.78 | LMNA (0.39) | LMNAALDH1A1SMN1; SMN2MEN1USP2 | |
| SCHEMBL9575958 | 0.76 | ALDH1A1 (0.41) | LMNAALDH1A1RARBSMN1; SMN2MEN1 | |
| SCHEMBL6027401 | 0.76 | NR5A1 (0.51) | RARB | |
| SCHEMBL9575960 | 0.75 | ACACB (0.41) | LMNAALDH1A1RARBSMN1; SMN2MEN1 | |
| SCHEMBL10454958 | 0.75 | SMN1; SMN2 (0.46) | LMNAALDH1A1SMN1; SMN2KMT2APPARA | |
| SCHEMBL9575718 | 0.75 | ALDH1A1 (0.39) | LMNAALDH1A1SMN1; SMN2MEN1USP2 | |
| SCHEMBL19644362 | 0.74 | SMN1; SMN2 (0.50) | LMNAALDH1A1SMN1; SMN2MEN1USP2 | |
| SCHEMBL788296 | 0.74 | SMN1; SMN2 (0.50) | LMNAALDH1A1SMN1; SMN2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281941-B1 | Coreactive photoinitiators | CIBA GEIGY AG (CH) | 1993-12-08 | — | — | EP | claimed |