Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455161 | 0.72 | ALDH1A1 (0.42) | SMN1; SMN2GAACA1CA2CA9 | |
| SCHEMBL5446136 | 0.69 | CA1 (0.45) | SMN1; SMN2GAACA1CA2LMNA | |
| SCHEMBL9577170 | 0.69 | CA1 (0.46) | GAACA12CA1CA2CA7 | |
| SCHEMBL1510877 | 0.67 | NMT1 (0.53) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL10455151 | 0.67 | LMNA (0.40) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL4175368 | 0.67 | CA1 (0.58) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL8677590 | 0.65 | F2 (0.32) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL11688100 | 0.63 | F2 (0.32) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9577227 | 0.62 | LMNA (0.40) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL20000064 | 0.62 | SMN1; SMN2 (0.37) | SMN1; SMN2GAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |