Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577237 | 0.82 | KEAP1 (0.50) | POLBKMT2AMEN1PKMHTT | |
| SCHEMBL9577174 | 0.79 | POLB (0.54) | POLBKMT2AMEN1PKMKEAP1 | |
| SCHEMBL2741008 | 0.77 | POLB (0.67) | POLBKMT2AMEN1PKMMAPT | |
| SCHEMBL8350452 | 0.75 | EDNRA (0.54) | KMT2AMEN1PKMMAPTHTT | |
| SCHEMBL7627388 | 0.74 | KEAP1 (0.67) | POLBKMT2AMEN1PKMKEAP1 | |
| SCHEMBL9577212 | 0.73 | HTT (0.50) | POLBKMT2AMEN1PKMHTT | |
| SCHEMBL9577222 | 0.71 | FABP4 (0.51) | KMT2AMEN1HTTFABP4FABP5 | |
| SCHEMBL19297161 | 0.71 | MEN1 (0.71) | POLBKMT2AMEN1PKMMAPT | |
| SCHEMBL11179607 | 0.68 | TSHR (0.54) | POLBKMT2AMEN1HTTFABP4 | |
| SCHEMBL21914643 | 0.68 | TSHR (0.61) | KMT2AMEN1PKMMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |