Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577212 | 0.91 | HTT (0.50) | FABP4FABP5KMT2AMEN1RXFP1 | |
| SCHEMBL9577222 | 0.88 | FABP4 (0.51) | FABP4FABP5KMT2AMEN1RXFP1 | |
| SCHEMBL9577174 | 0.86 | POLB (0.54) | KEAP1IL1RNERAP1FABP4FABP5 | |
| SCHEMBL9577208 | 0.84 | PTGES2 (0.41) | FABP4FABP5KMT2AMEN1RXFP1 | |
| SCHEMBL9577158 | 0.82 | POLB (0.45) | KEAP1IL1RNERAP1FABP4FABP5 | |
| SCHEMBL19297161 | 0.81 | MEN1 (0.71) | KEAP1IL1RNERAP1FABP4FABP5 | |
| SCHEMBL2741008 | 0.79 | POLB (0.67) | KEAP1IL1RNERAP1KMT2AMEN1 | |
| SCHEMBL9577102 | 0.78 | MCL1 (0.35) | FABP4FABP5KMT2AMEN1RXFP1 | |
| SCHEMBL9577188 | 0.78 | MCL1 (0.35) | FABP4FABP5KMT2AMEN1RXFP1 | |
| SCHEMBL7627388 | 0.76 | KEAP1 (0.67) | KEAP1IL1RNERAP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |