Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | IL1RN | P18510 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577133 | 0.89 | KEAP1 (0.57) | CA1CA2PKMALDH1A1MEN1 | |
| SCHEMBL9577117 | 0.73 | HTT (0.49) | CA1CA2PKMALDH1A1MEN1 | |
| SCHEMBL9577215 | 0.72 | CA12 (0.49) | CA1CA2PKMALDH1A1MEN1 | |
| SCHEMBL9577212 | 0.70 | HTT (0.50) | CA1CA2PKMALDH1A1CES1 | |
| SCHEMBL9535518 | 0.70 | NPSR1 (0.65) | CA1CA2PKMALDH1A1CES1 | |
| SCHEMBL6676861 | 0.68 | ALDH1A1 (0.56) | CA1CA2PKMALDH1A1MEN1 | |
| SCHEMBL6677818 | 0.68 | MAPT (0.51) | CA1CA2ALDH1A1HTTPOLB | |
| SCHEMBL9577130 | 0.67 | SMN1; SMN2 (0.36) | CA1CA2ALDH1A1GAAHTT | |
| SCHEMBL20847671 | 0.67 | CA1 (0.68) | CA1CA2PKMALDH1A1MEN1 | |
| SCHEMBL9577135 | 0.67 | HTT (0.56) | CA1CA2PKMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4981890-A | POLYHALOAROMATIC AND AROMATIC BIS-SULFONAMIDE | ETHYL CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| US-4959500-A | Polybrominated bis sulfonamides | ETHYL CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| US-4957958-A | IMPROVED MELT FLOW | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |