Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.57 |
| ▸ | IL1RN | P18510 | 1/20 | 0.57 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577159 | 0.89 | CA1 (0.45) | KEAP1IL1RNERAP1KMT2APKM | |
| SCHEMBL9577215 | 0.82 | CA12 (0.49) | KEAP1IL1RNERAP1KMT2APKM | |
| SCHEMBL9577191 | 0.81 | CA1 (0.43) | KMT2AMEN1ALDH1A1CA2CA1 | |
| SCHEMBL8939243 | 0.77 | KEAP1 (0.59) | KEAP1IL1RNERAP1KMT2APKM | |
| SCHEMBL6073362 | 0.75 | CA1 (0.62) | KEAP1IL1RNERAP1KMT2APKM | |
| SCHEMBL31575982 | 0.74 | GAA (0.52) | KEAP1IL1RNERAP1KMT2APKM | |
| SCHEMBL7579145 | 0.73 | PKM (0.83) | KEAP1IL1RNERAP1KMT2APKM | |
| SCHEMBL1857218 | 0.73 | KMT2A (0.74) | KEAP1IL1RNERAP1KMT2APKM | |
| SCHEMBL2741008 | 0.73 | POLB (0.67) | KEAP1IL1RNERAP1KMT2APKM | |
| SCHEMBL9577237 | 0.73 | KEAP1 (0.50) | KEAP1IL1RNERAP1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |