Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 5/20 | 0.42 |
| ▸ | DRD1 | P21728 | 4/20 | 0.42 |
| ▸ | DRD5 | P21918 | 4/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009571 | 0.80 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP11B2DRD2DRD3 | |
| SCHEMBL1143146 | 0.80 | METAP1 (0.47) | CYP19A1CYP11B1CYP11B2DRD2DRD3 | |
| SCHEMBL28123540 | 0.77 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2DRD2DRD3 | |
| SCHEMBL5413199 | 0.75 | PTGS2 (0.43) | DRD2DRD3DRD1DRD5CA12 | |
| SCHEMBL326339 | 0.73 | DRD2 (0.41) | CYP19A1CYP11B1CYP11B2DRD2DRD3 | |
| SCHEMBL9207075 | 0.73 | METAP1 (0.44) | CYP19A1CYP11B1CYP11B2METAP1GAA | |
| SCHEMBL3844075 | 0.73 | METAP1 (0.44) | CYP19A1CYP11B1CYP11B2DRD2DRD3 | |
| SCHEMBL8884488 | 0.71 | CA2 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1179742 | 0.70 | CYP11B2 (0.49) | CYP19A1CYP11B1CYP11B2DRD2DRD3 | |
| SCHEMBL28666103 | 0.70 | CYP11B2 (0.49) | CYP19A1CYP11B1CYP11B2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266723-A | Process for the preparation of optically active 2-aryl-alkanoic acids, especially 2-aryl-propionic acids | MEDICE, LTD., CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) | 1993-11-30 | — | — | US | claimed |