Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | ATF4 | P18848 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362200 | 0.76 | ATF4 (0.40) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL11738646 | 0.72 | NPSR1 (0.40) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL9768224 | 0.71 | MAOB (0.37) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL9783484 | 0.69 | MAPT (0.39) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL10507416 | 0.68 | MAOB (0.38) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL9768362 | 0.68 | ABCB11 (0.56) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL9665523 | 0.68 | MAOB (0.39) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL10863012 | 0.68 | PLA2G7 (0.37) | MAOBMAOACYP1A2CYP2C19 | |
| SCHEMBL10490027 | 0.68 | ABCB11 (0.36) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL10490023 | 0.68 | CPT1A (0.38) | ABCB11LMNAMAPTMAPK1CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264632-A | Fungicide intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-23 | — | — | US | disclosed |
| US-5208388-A | Chemical intermediates for heterocyclic fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | disclosed |
| EP-0351647-B1 | 2,2-DIFLUOROCYCLOPROPYL DERIVATES | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| US-5095147-A | Intermediates for fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| US-5047415-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| EP-0351649-A2 | 2,2-Dihalocyclopropyl-hydroxy-ethyl triazoles | BAYER AG (DE) | 1990-01-24 | — | — | EP | disclosed |
| EP-0351647-A2 | 2,2-Difluorocyclopropyl derivates | BAYER AG (DE) | 1990-01-24 | — | — | EP | disclosed |