Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5650328 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL9579270 | 0.80 | FAAH (0.44) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL18381443 | 0.79 | ITGB3 (0.45) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL19051509 | 0.78 | ITGB3 (0.54) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL485662 | 0.77 | FAAH (0.44) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL18402581 | 0.77 | FAAH (0.44) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL20663510 | 0.77 | TPSAB1 (0.43) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL20663511 | 0.76 | ITGB3 (0.45) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL11317564 | 0.74 | GNAI3 (0.43) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL11981542 | 0.74 | ITGB3 (0.46) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242919-A | Antiinflammatory agents or hypotensive agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| US-5055474-A | Antihypoxia, hypotensive, antiinflammatory agents; anoxia treatment | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0173331-B1 | 2,3-DIHYDRO-1H-INDENE DERIVATIVES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4895847-A | ANTIHYPOXIC, ANTIINFLAMMATORY, HYPOTENSIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| US-4788130-A | ANTIHYDOXIC, HYPOTENSIVE, ANTIINFLAMMATORY AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| EP-0173331-A2 | 2,3-Dihydro-1H-indene derivatives, a process for preparing them and pharmaceutical compositions containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |