Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPRS1 | P07814 | 4/20 | 0.67 |
| ▸ | DHODH | Q02127 | 5/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MC4R | P32245 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117430 | 0.84 | EPRS1 (0.79) | EPRS1DHODHHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL5792900 | 0.82 | DHODH (0.78) | EPRS1DHODHHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL18320678 | 0.81 | DHODH (0.70) | EPRS1DHODHHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL12237494 | 0.80 | RXFP1 (0.75) | EPRS1DHODHHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL117405 | 0.79 | EPRS1 (0.71) | EPRS1DHODHHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL117422 | 0.79 | PTGES (0.84) | EPRS1DHODHHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL117388 | 0.79 | EPRS1 (1.00) | EPRS1DHODHHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL5530291 | 0.78 | EPRS1 (0.85) | EPRS1DHODHHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL1899098 | 0.77 | RXFP1 (0.79) | EPRS1DHODHHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL29788463 | 0.77 | DHODH (0.80) | EPRS1DHODHTP53KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204329-A | 4-Quinoline carboxylic acid derivatives | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-04-20 | — | — | US | claimed |