Phosphoric Acid

Phosphoric Acid

SCHEMBL958094

O=P(O)(O)O.Oc1cccc(-c2ccccc2)c1O

nearest known ligand 0.56

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
HPGD P15428 4/20 0.56
HSD17B10 Q99714 4/20 0.56
BCL2L1 Q07817 1/20 0.56
HDAC4 P56524 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
HDAC6 Q9UBN7 1/20 0.53
HNF4A P41235 1/20 0.53
BACE1 P56817 3/20 0.46
PTPN5 P54829 3/20 0.46
ALOX15 P16050 3/20 0.42
LMNA P02545 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
RECQL P46063 2/20 0.42
ADAMTS4 O75173 1/20 0.42
EGFR P00533 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
FYN P06241 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL5597060 1.00 ALDH1A1 (0.56) ALDH1A1HPGDHSD17B10BCL2L1HDAC4
SCHEMBL29365218 0.89 ALDH1A1 (0.68) ALDH1A1HPGDHSD17B10BCL2L1HDAC4
SCHEMBL94298 0.89 ALDH1A1 (0.68) ALDH1A1HPGDHSD17B10BCL2L1HDAC4
Formaldehyde SCHEMBL11804579 0.88 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10BCL2L1HDAC4
Bicarbonate SCHEMBL27723911 0.88 HNF4A (0.62) ALDH1A1HPGDHSD17B10BCL2L1HDAC4
Biphenyl SCHEMBL25432905 0.87 ALDH1A1 (0.65) ALDH1A1HPGDHSD17B10BCL2L1HDAC4
Ammonia Solution, Strong SCHEMBL19405739 0.87 ALDH1A1 (0.65) ALDH1A1HPGDHSD17B10BCL2L1HDAC4
SCHEMBL2064516 0.87 ALDH1A1 (0.65) ALDH1A1HPGDHSD17B10BCL2L1HDAC4
Water SCHEMBL8773056 0.87 ALDH1A1 (0.65) ALDH1A1HPGDHSD17B10BCL2L1HDAC4
Methane SCHEMBL2283545 0.87 ALDH1A1 (0.65) ALDH1A1HPGDHSD17B10BCL2L1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11359033-B2 Flame retardant, method of manufacturing the same, resin composition of matter, and method of manufacturing the same SONY CORPORATION (JP) 2022-06-14 US disclosed
US-11261269-B2 Flame retardant, method of manufacturing the same, resin composition of matter, and method of manufacturing the same SONY CORPORATION (JP) 2022-03-01 US disclosed
US-10982021-B2 Flame retardant, method of manufacturing the same, resin composition of matter, and method of manufacturing the same SONY CORPORATION (JP) 2021-04-20 US disclosed
US-20200190232-A1 FLAME RETARDANT, METHOD OF MANUFACTURING THE SAME, RESIN COMPOSITION OF MATTER, AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2020-06-18 US disclosed
US-20200190231-A1 FLAME RETARDANT, METHOD OF MANUFACTURING THE SAME, RESIN COMPOSITION OF MATTER, AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2020-06-18 US disclosed
EP-2180033-B1 METHOD FOR PRODUCTION OF A FLAME RETARDANT AGENT SONY CORP (JP) 2017-11-15 EP disclosed
US-20170073437-A1 FLAME RETARDANT, METHOD OF MANUFACTURING THE SAME, RESIN COMPOSITION OF MATTER, AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2017-03-16 US disclosed
US-20110313110-A1 FLAME RETARDANT, METHOD OF MANUFACTURING THE SAME, RESIN COMPOSITION OF MATTER, AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-12-22 US disclosed
US-7868052-B2 Method for recycling recovered discs, flame retardant resin composition and flame retardant resin molded products SONY CORPORATION (JP) 2011-01-11 US disclosed
CN-1712199-B Method for recycling recovered discs, flame retardant resin composition and flame retardant resin molded products SONY CORP 2010-12-08 CN disclosed
EP-2180033-A1 FLAME RETARDANT AGENT, METHOD FOR PRODUCTION OF THE FLAME RETARDANT AGENT, RESIN COMPOSITION, AND METHOD FOR PRODUCTION OF THE RESIN COMPOSITION Sony Corporation (JP) 2010-04-28 EP disclosed
US-20050286397-A1 Method for recycling recovered discs, flame retardant resin composition and flame retardant resin molded products SONY CORPORATION (JP) 2005-12-29 US disclosed
CN-1712199-A Method for recycling recovered discs, flame retardant resin composition and flame retardant resin molded products SONY CORP (JP) 2005-12-28 CN disclosed
US-6454969-B1 POLYSILICATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-09-24 US disclosed
US-6316579-B1 MOLDABILITY, USEFUL FOR PRODUCING A MOLDED ARTICLE HAVING A GOOD EXTERNAL APPEARANCE AND IMPACT RESISTANCE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-11-13 US disclosed