Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.44 |
| ▸ | CNR1 | P21554 | 10/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587756 | 0.86 | TYMS (0.43) | CNR2KDM4EALDH1A1LMNAMAPK8 | |
| SCHEMBL9587882 | 0.79 | KMT2A (0.42) | CNR2CNR1MEN1KMT2A | |
| SCHEMBL9588736 | 0.78 | CNR2 (0.42) | CNR2LMNA | |
| SCHEMBL9587092 | 0.76 | PDK1 (0.36) | KDM4EMAPK8 | |
| SCHEMBL591137 | 0.76 | ALDH1A1 (0.51) | TSHRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL29331645 | 0.76 | S100B (0.58) | TSHRKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL9588510 | 0.75 | CRHBP (0.49) | MEN1ALDH1A1MAPTKMT2AMAPK8 | |
| SCHEMBL9586931 | 0.75 | KEAP1 (0.42) | CNR2CNR1KDM4EMEN1ALDH1A1 | |
| SCHEMBL29692342 | 0.74 | SLC2A1 (0.60) | CNR2 | |
| SCHEMBL9586987 | 0.74 | SLC2A1 (0.60) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013079-A1 | ANTIFOLATE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1993-07-08 | — | — | WO | disclosed |