Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792570 | 0.86 | L3MBTL1 (0.49) | HSP90AA1L3MBTL1TNKSTNKS2TDP1 | |
| SCHEMBL14709198 | 0.84 | L3MBTL1 (0.41) | HSP90AA1L3MBTL1TDP1ATMCNR1 | |
| SCHEMBL1347570 | 0.84 | KDM4E (0.41) | HSP90AA1L3MBTL1TDP1ATMCNR1 | |
| SCHEMBL8017131 | 0.83 | HSP90AA1 (0.63) | HSP90AA1L3MBTL1MAOBTDP1ATM | |
| SCHEMBL9586561 | 0.80 | HSP90AA1 (0.41) | HSP90AA1L3MBTL1TNKSTNKS2MAOB | |
| SCHEMBL9586564 | 0.80 | HSP90AA1 (0.41) | HSP90AA1L3MBTL1TNKSTNKS2MAOB | |
| SCHEMBL13178332 | 0.79 | KMT2A (0.50) | HSP90AA1L3MBTL1TNKSTDP1ATM | |
| SCHEMBL18859783 | 0.77 | TDP1 (0.40) | HSP90AA1L3MBTL1TNKSTNKS2MAOB | |
| SCHEMBL1505751 | 0.76 | L3MBTL1 (0.56) | HSP90AA1L3MBTL1TNKSTNKS2MAOB | |
| SCHEMBL1093585 | 0.75 | GPR3 (0.44) | L3MBTL1MAOBSMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160632-A1 | BISAMID-ZINKBASEN | LUDWIG MAXIMILIANS UNIVERSITAT MUNCHEN | 2010-06-24 | — | — | US | disclosed |
| US-5215994-A | Treating or preventing hypertension or heart failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5210092-A | Hypotensive agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0480204-A1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160632-A1 | BISAMID-ZINKBASEN | ZFX, ZRANB2, MLX | HSP90AA1 3878/4885L3MBTL1 685/4885TNKS 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.