Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PMM2 | O15305 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792570 | 0.86 | L3MBTL1 (0.49) | KDM4EL3MBTL1HSP90AA1TDP1ATM | |
| SCHEMBL9587486 | 0.84 | HSP90AA1 (0.44) | KDM4EL3MBTL1HSP90AA1NPSR1MAPT | |
| SCHEMBL14709198 | 0.84 | L3MBTL1 (0.41) | KDM4EL3MBTL1HSP90AA1NPSR1MAPT | |
| SCHEMBL8017131 | 0.80 | HSP90AA1 (0.63) | KDM4EL3MBTL1HSP90AA1MAPTSMN1; SMN2 | |
| SCHEMBL11558775 | 0.77 | KDM4E (0.39) | KDM4EL3MBTL1GABRA1GABRA5NPSR1 | |
| SCHEMBL28538104 | 0.75 | PTGS2 (0.44) | KDM4EL3MBTL1GABRA1GABRA5TDP1 | |
| SCHEMBL15200639 | 0.75 | SLC9A1 (0.40) | KDM4EL3MBTL1GABRA1GABRA5MAPT | |
| SCHEMBL28521550 | 0.75 | KDM4E (0.41) | KDM4EL3MBTL1HSP90AA1GABRA1GABRA5 | |
| SCHEMBL28519702 | 0.75 | TDP1 (0.42) | KDM4EL3MBTL1HSP90AA1GABRA1GABRA5 | |
| SCHEMBL11557192 | 0.75 | GABRA1 (0.53) | KDM4EL3MBTL1GABRA1GABRA5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396337-B1 | PREPARATION AND USE OF ZINC-AMIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-13 | — | — | EP | claimed |
| EP-2396337-A1 | PRODUCTION AND USE OF ZINC AMIDES | Ludwig-Maximilians-Universität München (DE) | 2011-12-21 | — | — | EP | claimed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | claimed |
| WO-2010092096-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-08-19 | — | — | WO | claimed |
| WO-2006018544-A1 | COMPOSITION CONTAINING A THIOPHENIC OR BENZOTHIOPHENIC COMPOUND AND EXHIBITING A PUMP NORA INHIBITING ACTIVITY | UNIVERSITE CLAUDE BERNARD LYON I (FR) | 2006-02-23 | — | — | WO | claimed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688701-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2017-06-27 | — | — | US | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| US-20160215000-A1 | Production And Use Of Zinc Amides | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-28 | — | — | US | disclosed |
| EP-2396337-B1 | PREPARATION AND USE OF ZINC-AMIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2016-07-13 | — | — | EP | disclosed |
| US-9334237-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2016-05-10 | — | — | US | disclosed |
| US-9334237-B2 | Production and use of zinc amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2016-05-10 | — | — | US | disclosed |
| EP-2396337-A1 | PRODUCTION AND USE OF ZINC AMIDES | Ludwig-Maximilians-Universität München (DE) | 2011-12-21 | — | — | EP | disclosed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010092096-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010092096-A1 | PRODUCTION AND USE OF ZINC AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215000-A1 | Production And Use Of Zinc Amides | SCLY, CBR3, SCO2 | KDM4E 2931/4885L3MBTL1 1251/4885HSP90AA1 3899/4885 |
| US-20110288296-A1 | PRODUCTION AND USE OF ZINC AMIDES | GLRX3, SCLY, SFXN1 | KDM4E 3350/4885L3MBTL1 1395/4885HSP90AA1 2426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.