Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716583 | 0.90 | MAPT (0.56) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10719148 | 0.81 | MAPT (0.55) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10728354 | 0.79 | MAPT (0.46) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10730881 | 0.78 | MAPT (0.54) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL10716646 | 0.77 | MAPT (0.50) | MAPTKDM4EKMT2AHSD11B1RAB9A | |
| SCHEMBL10725434 | 0.76 | MAPT (0.49) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL10730781 | 0.75 | MAPT (0.58) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL10725561 | 0.73 | PKM (0.49) | MAPTKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL10716650 | 0.73 | MAPT (0.78) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10717891 | 0.73 | MAPT (1.00) | MAPTALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |