Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26746 | 0.86 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3KIF11ACACB | |
| SCHEMBL3842131 | 0.78 | PPARA (0.40) | SLC6A2SLC6A4SLC6A3KIF11ACACB | |
| SCHEMBL198046 | 0.78 | RIPK1 (0.43) | SLC6A2SLC6A4SLC6A3KIF11ACACB | |
| SCHEMBL19339945 | 0.78 | MAPT (0.44) | SLC6A2SLC6A4SLC6A3KIF11ACACB | |
| SCHEMBL18866585 | 0.78 | MAPT (0.44) | SLC6A2SLC6A4SLC6A3KIF11ACACB | |
| SCHEMBL317934 | 0.76 | ACHE (0.50) | SLC6A2SLC6A4SLC6A3KIF11ACACB | |
| SCHEMBL5285766 | 0.76 | CA1 (0.61) | MEN1KMT2AKDM4ECYP3A4MAPT | |
| SCHEMBL11378368 | 0.75 | NQO1 (0.40) | SLC6A2SLC6A4SLC6A3KIF11ACACB | |
| SCHEMBL5392701 | 0.75 | SCN10A (0.32) | PPARAPPARG | |
| SCHEMBL1006518 | 0.74 | ALDH1A1 (0.42) | SLC6A2SLC6A4SLC6A3KIF11ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276411-B | Solid phase synthesis method of cyclic peptide compound containing trithioether bond | 北京大学深圳研究生院 | 2024-02-09 | — | — | CN | claimed |
| CN-114685608-A | Cyclic peptide compound containing trithioether bond or derivative thereof, and synthetic method and application thereof | 北京大学深圳研究生院 | 2022-07-01 | — | — | CN | claimed |
| CN-114276411-A | Solid phase synthesis method of cyclic peptide compound containing trithioether bond | 北京大学深圳研究生院 | 2022-04-05 | — | — | CN | claimed |
| US-20210122713-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2021-04-29 | — | — | US | claimed |
| EP-3672960-A2 | COMPOUNDS, SALTS THEREOF AND THEIR USE FOR THE TREATMENT OF DISEASES | Acadia Pharmaceuticals Inc. (US) | 2020-07-01 | — | — | EP | claimed |
| WO-2019040104-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | claimed |
| EP-1662877-B1 | 6-HALOGENO-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINES FOR COMBATING ANIMAL PESTS | MERIAL LTD (US) | 2014-12-17 | — | — | EP | claimed |
| US-8669253-B2 | Methods for treating glaucoma and macular degeneration | DUKE UNIVERSITY (US) | 2014-03-11 | — | — | US | claimed |
| CN-101495464-B | Prokineticin 1 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2014-03-05 | — | — | CN | claimed |
| CN-103396398-A | Prokineticin 1 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2013-11-20 | — | — | CN | claimed |
| EP-0309913-B1 | Fungicidal N-substituted 3-aryl-pyrrolidine derivatives | BASF AG (DE) | 1994-06-15 | — | — | EP | claimed |
| WO-1994000461-A1 | INHIBITORS OF RETROVIRAL PROTEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-06 | — | — | WO | claimed |
| US-5068245-A | For treatment of plants | BASF AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | claimed |
| US-5051409-A | Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | claimed |
| EP-0435059-A1 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-03 | — | — | EP | claimed |
| EP-0428849-A2 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | claimed |
| CN-1050545-A | Inhibitors of post-infective viral proteases | HOECHST AG (DE) | 1991-04-10 | — | — | CN | claimed |
| EP-0369335-A2 | 2-Aminodecaline derivatives and their use | BASF Aktiengesellschaft (DE) | 1990-05-23 | — | — | EP | claimed |
| EP-0309913-A2 | Fungicidal N-substituted 3-aryl-pyrrolidine derivatives | BASF Aktiengesellschaft (DE) | 1989-04-05 | — | — | EP | claimed |
| US-4181733-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122713-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | SLC10A1, VHL, CYP11B2 | SLC6A2 290/4885SLC6A4 853/4885SLC6A3 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.