Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18210775 | 0.93 | TEAD4 (0.54) | ACHETDP1TSHRCYP3A4TEAD4 | |
| SCHEMBL14465631 | 0.93 | ACHE (0.44) | ACHETDP1TSHRCYP3A4TEAD4 | |
| SCHEMBL18715597 | 0.89 | TSHR (0.46) | ACHETDP1TSHRCYP3A4TEAD4 | |
| SCHEMBL26746 | 0.88 | SLC6A2 (0.44) | ACHETSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL25156564 | 0.87 | TEAD4 (0.48) | ACHETDP1TEAD4ALDH1A1POLB | |
| SCHEMBL6367283 | 0.87 | ACHE (0.39) | ACHETDP1TSHRCYP3A4TEAD4 | |
| SCHEMBL22688263 | 0.87 | MLYCD (0.43) | ACHETDP1TSHRCYP3A4TEAD4 | |
| SCHEMBL21540971 | 0.83 | GAA (0.61) | ACHETDP1ALDH1A1POLBMAPT | |
| SCHEMBL17302417 | 0.83 | LMNA (0.61) | ACHETDP1TSHRCYP3A4ALDH1A1 | |
| SCHEMBL8521425 | 0.83 | RELA (0.42) | ACHETDP1TSHRCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 518 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670108-A | Ether compounds as volatiles for treating amino acid based substrates such as skin and hair | 迈图高新材料有限责任公司 | 2023-08-29 | — | — | CN | claimed |
| CN-103420810-A | Preparation method for polymerization-type asymmetric hindered phenol anti-oxidant resins | CHINA PETROLEUM & CHEMICAL | 2013-12-04 | — | — | CN | claimed |
| EP-2585069-A1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN | Janssen Pharmaceutica, N.V. (BE) | 2013-05-01 | — | — | EP | claimed |
| EP-1973886-B1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2013-02-27 | — | — | EP | claimed |
| US-20120157370-A1 | WASHING PERFORMANCE USING RADICAL TRAPS | HENKEL AG & CO. KGAA (DE) | 2012-06-21 | — | — | US | claimed |
| WO-2012006004-A1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN | JANSSEN PHARMACEUTICA NV (BE) | 2012-01-12 | — | — | WO | claimed |
| US-20110319400-A1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN | JANSSEN PHARMACEUTICA, NV (BE) | 2011-12-29 | — | — | US | claimed |
| EP-2385042-A1 | Prokineticin 1 receptor antagonists | Janssen Pharmaceutica N.V. (BE) | 2011-11-09 | — | — | EP | claimed |
| US-8039028-B2 | Use of an extract of the orchid Vanda coerulea as a skin hydrating agent | LVMH REACHERCHE (FR) | 2011-10-18 | — | — | US | claimed |
| US-7902358-B2 | Gastrointestinal disorders; inflammatory bowel disorders; gastroesophageal reflux, constipation; diarrhea | JANSSEN PHARMACEUTICA NV (BE) | 2011-03-08 | — | — | US | claimed |
| US-7611644-B2 | Core-shell structure metal nanoparticles and its manufacturing method | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2009-11-03 | — | — | US | claimed |
| US-20090171046-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | claimed |
| EP-2075267-A2 | Process for producing polydienes | Bridgestone Corporation (JP) | 2009-07-01 | — | — | EP | claimed |
| US-20080287445-A1 | Prokineticin 2 receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-11-20 | — | — | US | claimed |
| US-20080269225-A1 | Prokineticin 1 receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-30 | — | — | US | claimed |
| US-20070212562-A1 | Core-shell structure metal nanoparticles and its manufacturing method | SAMSUNG ELECTRO-MECANICS CO., LTD. (KR) | 2007-09-13 | — | — | US | claimed |
| CN-1656178-A | Oil-soluble pigment compositions | PHARES PHARM RES NV (NL) | 2005-08-17 | — | — | CN | claimed |
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | claimed |
| EP-0025883-B1 | ELECTROCHEMICAL PROCESS FOR THE PREPARATION OF 4-TERT.-BUTOXY-BENZALDEHYDE-DIALKYLACETALS, THEIR USE AND 4-TERT.-BUTOXY-BENZALDEHYDE-DIMETHYLACETAL | BASF Aktiengesellschaft (DE) | 1983-01-12 | — | — | EP | claimed |
| EP-0025883-A1 | Electrochemical process for the preparation of 4-tert.-butoxy-benzaldehyde-dialkylacetals, their use and 4-tert.-butoxy-benzaldehyde-dimethylacetal | BASF Aktiengesellschaft (DE) | 1981-04-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319400-A1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN | PROKR1, OPRL1, PROKR2 | ACHE 502/4885TDP1 3266/4885TSHR 1432/4885 |
| US-20080269225-A1 | Prokineticin 1 receptor antagonists | PROKR1, PROKR2, GIPR | ACHE 4205/4885TDP1 4130/4885TSHR 228/4885 |
| US-20120157370-A1 | WASHING PERFORMANCE USING RADICAL TRAPS | MPO, DNASE1, PLD4 | ACHE 713/4885TDP1 201/4885TSHR 3393/4885 |
| US-20080287445-A1 | Prokineticin 2 receptor antagonists | PROKR2, PROKR1, GIPR | ACHE 3869/4885TDP1 4548/4885TSHR 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.