Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 13/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957882 | 0.84 | MAP4K4 (0.54) | — | |
| SCHEMBL959319 | 0.81 | MRGPRX4 (0.61) | NPC1RAB9ACNR1 | |
| SCHEMBL958072 | 0.80 | L3MBTL1 (0.51) | CNR2NPC1RAB9ASMN1; SMN2CNR1 | |
| SCHEMBL960594 | 0.78 | CTSL (0.44) | NPC1RAB9ASMN1; SMN2CNR1 | |
| SCHEMBL958854 | 0.78 | CNR2 (0.59) | CNR2NPC1RAB9A | |
| SCHEMBL956572 | 0.77 | GPR52 (0.48) | CNR1 | |
| SCHEMBL962349 | 0.76 | GPR52 (0.45) | CNR2SMN1; SMN2CNR1 | |
| SCHEMBL957915 | 0.73 | MRGPRX4 (0.50) | CNR1 | |
| SCHEMBL958823 | 0.72 | MRGPRX4 (0.49) | — | |
| SCHEMBL14152082 | 0.72 | CNR2 (1.00) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | claimed |
| EP-2253618-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | GPR4, NR3C2, NR5A2 | CNR2 36/4885NPC1 2153/4885RAB9A 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.