Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 7/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593290 | 0.92 | LMNA (0.62) | LMNANQO2KDM4EALDH1A1MAPT | |
| SCHEMBL9595057 | 0.92 | NQO2 (0.50) | LMNANQO2KDM4EALDH1A1MAPT | |
| SCHEMBL22791812 | 0.91 | LMNA (0.50) | LMNAKDM4EALDH1A1MAPTMAOA | |
| SCHEMBL27961718 | 0.87 | MAOA (0.67) | LMNANQO2KDM4EALDH1A1MAPT | |
| SCHEMBL9593514 | 0.87 | MAOA (0.67) | LMNANQO2KDM4EALDH1A1MAPT | |
| SCHEMBL9593843 | 0.87 | LMNA (0.53) | LMNANQO2KDM4EALDH1A1MAPT | |
| SCHEMBL9594512 | 0.85 | KDM4E (0.49) | LMNANQO2KDM4EALDH1A1PKM | |
| SCHEMBL26356180 | 0.85 | KDM4E (0.52) | LMNANQO2KDM4EALDH1A1PKM | |
| SCHEMBL15397410 | 0.81 | MPO (0.45) | LMNANQO2KDM4EALDH1A1MAPT | |
| SCHEMBL9594424 | 0.81 | LMNA (0.47) | LMNANQO2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | claimed |
| US-5229395-A | Potential anticancer agents derived from acridine | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1993-07-20 | — | — | US | disclosed |
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | disclosed |