Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.60 |
| ▸ | CES1 | P23141 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383906 | 0.79 | LMNA (0.60) | LMNACES2CES1MAPK1L3MBTL1 | |
| SCHEMBL11433746 | 0.75 | LMNA (0.56) | LMNACES2CES1MAPK1L3MBTL1 | |
| Benzoin SCHEMBL5833429 | 0.75 | CES2 (1.00) | LMNACES2CES1MAPK1L3MBTL1 | |
| SCHEMBL4631540 | 0.75 | LMNA (0.56) | LMNACES2CES1MAPK1L3MBTL1 | |
| Benzoin SCHEMBL145 | 0.75 | CES2 (1.00) | LMNACES2CES1MAPK1L3MBTL1 | |
| Benzoin SCHEMBL901258 | 0.75 | CES2 (1.00) | LMNACES2CES1MAPK1L3MBTL1 | |
| Benzoin SCHEMBL10665271 | 0.75 | CES2 (1.00) | LMNACES2CES1MAPK1L3MBTL1 | |
| Benzoin SCHEMBL2025536 | 0.75 | CES2 (1.00) | LMNACES2CES1MAPK1L3MBTL1 | |
| SCHEMBL10536611 | 0.75 | LMNA (0.62) | LMNACES2CES1MAPK1L3MBTL1 | |
| SCHEMBL10865453 | 0.75 | LMNA (0.62) | LMNACES2CES1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217845-A | 9-Arylacridine as photoinitiator | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | disclosed |