Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596263 | 1.00 | NOS3 (0.46) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9595427 | 0.83 | KMT2A (0.44) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9595419 | 0.83 | KMT2A (0.44) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4855895 | 0.73 | RAB9A (0.61) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22087559 | 0.72 | MAPT (0.40) | MAPTALDH1A1GAAPOLBDRD2 | |
| SCHEMBL7432141 | 0.70 | POLB (0.57) | MAPTALDH1A1CRHBPCRHR2GAA | |
| SCHEMBL16879478 | 0.70 | ALDH1A1 (0.59) | MAPTALDH1A1GAAPOLBDRD2 | |
| SCHEMBL4863537 | 0.70 | KMT2A (0.55) | NOS3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9596474 | 0.69 | ALDH1A1 (0.38) | ALDH1A1GAAPOLBRAB9ANPC1 | |
| SCHEMBL9596468 | 0.69 | ALDH1A1 (0.38) | ALDH1A1GAAPOLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5272164-A | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |