Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.63 |
| ▸ | RARG | P13631 | 11/20 | 0.63 |
| ▸ | RARA | P10276 | 9/20 | 0.63 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | RXRA | P19793 | 12/20 | 0.59 |
| ▸ | RXRB | P28702 | 11/20 | 0.59 |
| ▸ | RXRG | P48443 | 9/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | BLVRB | P30043 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748608 | 0.78 | RXRA (0.46) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL29355626 | 0.78 | RARB (1.00) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL726740 | 0.78 | RARB (1.00) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL7621355 | 0.76 | RARA (0.82) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL28513667 | 0.75 | RNASEH1 (0.55) | MEN1KMT2ATSHR | |
| SCHEMBL29827631 | 0.74 | RARB (0.81) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL846110 | 0.74 | RARB (0.81) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL9446600 | 0.74 | RARA (0.78) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL8317306 | 0.73 | RARB (0.68) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL9125988 | 0.73 | RARB (0.64) | RARBRARGRARACYP26A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993006086-A1 | RETINOIDS AND THEIR USE IN TREATING SKIN DISEASES AND LEUKEMIA | PFIZER INC. (US) | 1993-04-01 | — | — | WO | disclosed |