Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597080 | 0.91 | ALDH1A1 (0.45) | ALDH1A1NPSR1TSHRSMN1; SMN2RAB9A | |
| SCHEMBL9263753 | 0.90 | ALDH1A1 (0.48) | ALDH1A1NPSR1TSHRSMN1; SMN2RAB9A | |
| SCHEMBL9219866 | 0.80 | TMEM97 (0.49) | — | |
| SCHEMBL9221444 | 0.79 | SIGMAR1 (0.49) | ALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL9597086 | 0.79 | TMEM97 (0.51) | — | |
| SCHEMBL9213014 | 0.76 | HTR1A (0.49) | — | |
| SCHEMBL9215613 | 0.76 | EGFR (0.48) | — | |
| SCHEMBL9589803 | 0.75 | KDM4E (0.58) | ALDH1A1NPSR1TSHRMAPK1LMNA | |
| SCHEMBL6008209 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2HPGDKDM4EKMT2A | |
| SCHEMBL9215528 | 0.74 | HTR7 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242923-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-09-07 | — | — | US | disclosed |
| US-5130311-A | Analgesics or antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1992-07-14 | — | — | US | disclosed |